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  • We are a global community spreading awareness, resources, and information about Lyme Disease. We welcome submissions and wou ld love to share your resources, stories, and local events about Lyme. We support and promote the growing conversation about Lyme through all kinds different media forms – radio, social media, blogs, books, TV, news, etc.
Much controversy exists regarding whether recurrent Lyme disease is due to reinfection or relapse. In this analysis of 22 paired episodes of Lyme disease, reinfection appears to be the mechanism fo...

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  • The pathogenic spirochete Borrelia burgdorferi senses and responds to changes in the environment, including changes in nutrient availability, throughout its enzootic cycle in Ixodes ticks and vertebrate hosts. This study examined the role of DnaK suppressor protein (DksA) in the transcriptional response of B. burgdorferi to starvation. Wild-type and dksA mutant B. burgdorferi strains were ...
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  • Lyme neuroborreliosis is likely caused by inflammatory effects of the tick-borne spirochete Borrelia burgdorferi on the nervous system. Microglia, the resident macrophage cells within the central nervous system (CNS), are important in initiating an immune response to microbial products.

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    Oct 18, 2011 · Previous studies and our further ChIP analyses and global RNA sequencing indicate that both BpaB and EbfC bind sites throughout the borrelial genome, in addition to erp operator elements, and control production of numerous other bacterial genes (44; our unpublished results). Defining the mechanisms by which the Lyme disease spirochete controls ...

    Oct 21, 2020 · SAINT-HERBLAIN, France I October 20, 2020 I Valneva SE (“Valneva”), a specialty vaccine company focused on prevention of diseases with major unmet needs, today announced positive initial results for its second Phase 2 study (VLA15-202) of Lyme disease vaccine candidate VLA15.

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    Lyme disease, a tick-borne infection caused by Borrelia burgdorferi [], results in >30 000 reported cases each year in the United States [] and approximately 500 cases annually in Canada []—figures that likely underestimate the true incidence of the disease.

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    Information on Lyme disease. Provided by the U.S. Centers for Disease Control and Prevention. There is no credible scientific evidence that Lyme disease is spread through sexual contact.

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